Cadeia de frio farmacêutica e novas ferramentas tecnológicas: uma revisão sistemática
DOI:
https://doi.org/10.14295/transportes.v29i1.2197Palavras-chave:
Cadeia de suprimentos, farmacêutica, Sistema de monitoramento, Logística, Revisão da literaturaResumo
A cadeia de frio farmacêutica ou pharmaceutical cold chain (PCC) lida com requisitos operacionais de logística específicos, relacionados à qualidade, segurança e regulamentações do produto, o que torna complexo o processo de gerenciamento da cadeia de suprimentos. Além disso, o crescimento do mercado da indústria farmacêutica aumenta a conscientização, em termos de monitoramento e controle de temperatura de mercadorias, dos processos de armazenamento e transporte em toda a rede. Este estudo fornece uma nova abordagem para o PCC, com base em uma revisão sistemática da literatura e extensa análise dos principais aspectos que influenciam os processos da cadeia de suprimentos. As principais conclusões destacam o recente progresso da pesquisa mundial sobre os assuntos relacionados ao PCC, bem como os desafios envolvidos e seus avanços tecnológicos associados, com base em três atributos (características do produto, recursos do veículo e experiência do fornecedor de serviços de logística) e, finalmente, o impacto das tecnologias e seu potencial utilização para melhorar o processo de tomada de decisão em operações integradas da cadeia de frio.
Downloads
Referências
Abdellah, A.; M. Noordin e W. Ismail (2015) Importance and globalization status of good manufacturing practice require-ments for pharmaceutical excipients. Saudi Pharmaceutical Journal, v. 23, n. 1, p. 9-13. DOI: 10.1016/j.jsps.2013.06.003.
Aguas, J.; W. Jaimes e E. Escamilla (2016) Drug Supply Network Coordination: A Case Applied to the Colombian Health Sector. Revista EIA/English version, v. 13, n. 25, p. 171-183. Disponível em: <http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S1794-12372016000100013&lng=en&nrm=iso>. ISSN: 1794-1237>. (Acesso em 10/112018).
Agyekum, P. (2012) Public health challenges in the supply chain management of cold chain medicines in the greater accra region. Thesis (Masters). Kwame Nkrumah University of Science and Technology.
Asamoah, D.; J. Annan e S. Nyarko (2012) AHP approach for supplier evaluation and selection in a pharmaceutical manufac-turing firm in Ghana. International Journal of Business and Management, v. 7, n. 10, p. 49. DOI: 10.5539/ijbm.v7n10p49
Allen, L. e H. Ansel (2013) Ansel's pharmaceutical dosage forms and drug delivery systems. Lippincott Williams & Wilkins. ISBN: 978-1-4511-8876-9.
Arya, A.; A. Chandra; V. Sharma e K. Pathak (2012) Fast dissolving oral films: an innovative drug delivery system and dosage form. International Journal of Chem Tech Research, v. 2, n. 1, p. 576-583. ISSN: 0974-4290. Disponível em: <http://www.ijrrpas.com/article/fast-dissolving-oral-films-innovative-drug-delivery-system>. (Acesso em 10/11/2018).
Aung, M.; F. Liang; Y. Chang; et al. (2011) RFID-and WSN-based intelligent cold chain management. International Journal of Manufacturing Research, v. 6, n. 2, p. 91-109. DOI: 10.1504/IJMR.2011.040005.
Baboli, A.; J. Fondrevelle; R. Tavakkoli-Moghaddam e A. Mehrabi (2011) A replenishment policy based on joint optimization in a downstream pharmaceutical supply chain: centralized vs. decentralized replenishment. The International Journal of Advanced Manufacturing Technology, v. 57, n. 1-4, p. 367-378. DOI: 10.1007/s00170-011-3290-x.
Bate, R. e K. Hess (2010) Anti-malarial drug quality in Lagos and Accra-a comparison of various quality assessments. Malaria journal, v. 9, n. 1, p. 157. DOI: 10.1186/1475-2875-9-157.
Bauer, E. (2016) Pharmaceutical packaging handbook. CRC Press. ISBN:978-0-470-25958-0.
Bertoldi, A.; A. Helfer; A. Camargo; et al. (2012) Is the Brazilian pharmaceutical policy ensuring population access to essential medicines?. Globalization and health, v. 8, n. 1, p. 6. DOI: 10.1186/1744-8603-8-6.
Bijwaard, D.; W. Van Kleunen; P. Havinga; et al., (2011) Industry: Using dynamic WSNs in smart logistics for fruits and phar-macy. Proceedings of the 9th ACM Conference on Embedded Networked Sensor Systems p. 218-231. DOI: 10.1145/2070942.2070965.
Bosona, T. e G. Gebresenbet (2013) Food traceability as an integral part of logistics management in food and agricultural supply chain. Food control, v. 33, n. 1, p. 32-48. DOI: 10.1016/j.foodcont.2013.02.004.
Caroline, N.; B. Elling e M. Smith (2011) Nancy Caroline's emergency care in the streets. Jones & Bartlett Publishers. ISBN: 978-0-7637-4412-0.
Castillo, M.; V. Antúnez Saiz e E. Martínez (2017) Mejora del proceso de almacenamiento y distribución de productos comer-ciales basada en gestión de riesgos en una organización biofarmacéutica cubana. Cofin Habana, v. 11, n. 1, p. 1-10. ISSN 2073-6061.
Chaudhari, S. e P. Patil (2012) Pharmaceutical excipients: a review. Int. J. Adv. Pharm. Biol. Chem, v. 1 n. 1, p. 21-34. Disponível em: <http://www.ijapbc.com/files/4.pdf. ISSN: 2277-4688>. (Acesso em 10/11/2018).
Chavan, M.; V. Suryawanshi e S. Sankpal (2014) AVR Microcontroller Based Temperature Control System with Real Time Data Logger. International Journal of Advance Research in Computer Science and Management Studies, v. 2, n. 11, p. 51-57. Disponível em: <http://www.ijarcsms.com/docs/paper/volume2/issue11/V2I11-0018.pdf. E-ISSN: 2321-7782>. (Acesso em 10/11/2018).
Chen, K. e Y. Shaw (2011) Applying back propagation network to cold chain temperature monitoring. Advanced Engineering Informatics, v. 25, n.1, p. 11-22. DOI: 10.1016/j.aei.2010.05.003.
Chircu, A.; E. Sultanow e S. Saraswat (2014) Healthcare RFID in Germany: an integrated pharmaceutical supply chain per-spective. Journal of Applied Business Research, v. 30 N. 3, p. 737. DOI: 10.19030/jabr.v30i3.8559.
Chowdary, B. e D. George (2011) Improvement of manufacturing operations at a pharmaceutical company: a lean manufac-turing approach. Journal of Manufacturing Technology Management, v. 23, n. 1, p. 56-75. DOI: 10.1108/17410381211196285.
Chung, C. e I. Peng (2018) Based on RFID Positioning System with Wireless Medical Care Environment Simulation. Proceed-ings of the International Symposium on Computer, Consumer and Control, p. 177-180. DOI: 10.1109/IS3C.2018.00052.
Çakici, Ö.; H. Groenevelt e A. Seidmann (2011) Using RFID for the management of pharmaceutical inventory system optimiza-tion and shrinkage control. Decision Support Systems, v. 51, n. 4, p. 842-852. DOI: 10.1016/j.dss.2011.02.003.
Dadfar, H. e S. Brege (2012) Differentiation by improving quality of services at the last touch point: the case of Tehran phar-macies. International Journal of Quality and Service Sciences, v. 4, n. 4, p. 345-363. DOI 10.1108/17566691211288331.
Dallais, A.; T. Dubreuil; D. Pathier e M. Youbi-Idrissi (2014) Flowmeter for two-phase gas/liquid cryogenic fluids. U.S. Patent Application n. 14/122,137. Disponível em: <https://patentimages.storage.googleapis.com/8d/00/b3/bdf6ac3b152ae7/US20140238124A1.pdf>. (Acesso em 10/11/2018).
Danielis, R.; E. Maggi; L. Rotaris e E. Valeri (2013) Urban freight distribution: urban supply chains and transportation poli-cies. In Freight transport modelling (p. 377-403). Emerald Group Publishing Limited. DOI: 10.1108/9781781902868-019.
De Vries, J. (2011) The shaping of inventory systems in health services: A stakeholder analysis. International Journal of Pro-duction Economics, v. 133, n. 1, p. 60-69. DOI: 10.1016/j.ijpe.2009.10.029.
De Weerdt, E.; S. Simoens; L. Hombroeckx; M. Casteels e I. Huys (2015) Causes of drug shortages in the legal pharmaceutical framework. Regulatory Toxicology and Pharmacology, v. 71, n. 2, p. 251-258. DOI: 10.1016/j.yrtph.2015.01.005.
Defraeye, T.; P. Cronjé; T. Berry; U. Opara; A. East; et al. (2015) Towards integrated performance evaluation of future packag-ing for fresh produce in the cold chain. Trends in food science & technology, v. 44, n. 2, p. 201-225. DOI: 10.1016/j.tifs.2015.04.008.
Donno, D.; G. Beccaro; A. Cerutti; M. Mellano e G. Bounous (2015) Bud Extracts as New Phytochemical Source for Herbal Preparations—Quality Control and Standardization by Analytical Fingerprint, InTech, ISBN: 978-953-51-2170-1.
Duan, J.; Y. Jiang; G. Cherian e Y. Zhao (2010) Effect of combined chitosan-krill oil coating and modified atmosphere packag-ing on the storability of cold-stored lingcod (Ophiodon elongates) fillets, Food Chemistry, v. 122, n. 4, p. 1035-1042. DOI: 10.1016/j.foodchem.2010.03.065.
Duran, D. (2011) Análisis fisicoquímico de productos farmacéuticos en las diferentes etapas del proceso de la industria far-macéutica. Thesis (Doctoral), Espanha.
Elder, D.; M. Kuentz e R. Holm (2016) Pharmaceutical excipients—quality, regulatory and biopharmaceutical considerations, European Journal of Pharmaceutical Sciences, v. 87, p. 88-99. DOI: 10.1016/j.ejps.2015.12.018.
El Shinnawy, A. (2012) Understanding the impact of protection on manufacturing efficiency levels and relative pharmaceu-tical prices evidence from Egypt’s generics pharmaceutical industry Thesis (Doctoral), London School of Economics and Political Science.
Enyinda, C.; C. Mbah e A. Ogbuehi (2010) An empirical analysis of risk mitigation in the pharmaceutical industry supply chain: A developing-country perspective. Thunderbird International Business Review, v. 52, n. 1, p. 45–54. DOI:10.1002/tie.20309.
Foroutan, B. e R. Foroutan (2014) Household storage of medicines and self-medication practices in south-east Islamic Re-public of Iran. EMHJ-Eastern Mediterranean Health Journal, v. 20, n. 9, p. 547-553. Disponível em: <https://apps.who.int/iris/bitstream/handle/10665/272512/EMHJ_2014_20_9_547_553.pdf?sequence=1&isAllowed=y>. ISSN: 1020-3397. (Acesso em 10/11/2018).
Ghaibi, S.; H. Ipema; R. Soni; D. Bartolo e C. Mancuso (2014) Special Feature Light-Sensitive Injectable Prescription Drugs. Hosp Pharm, v. 49, n. 2, p. 136–163. DOI: /10.1310/hpj4902-136.
Gin, B.; M. Farid e P. Bansal (2010) Effect of door opening and defrost cycle on a freezer with phase change panels. Energy Conversion and Management, v.51, n.12, p. 2698-2706. DOI: 10.1016/j.enconman.2010.06.005.
Göllü, E. (2017) Impact of product originality and supply chain structure on market share in the pharmaceutical industry. International Journal of Pharmaceutical and Healthcare Marketing, v. 11, n. 1, p. 60–79. DOI: 10.1108/IJPHM-01-2016-0009.
Goncharuk, A. e M. Getman (2014) Benchmarking to improve a strategy and marketing in pharmaceuticals. Benchmarking: An International Journal, v. 21, n. 3, p. 364-385. DOI: 10.1108/BIJ-06-2012-0041.
Board, Irish Medicines (2006) Guide to control and monitoring of storage and transportation temperature conditions for medicinal products and active substances. Disponível em: https:. (Acesso em10 Nov. 2018).
Hatchett, R. (2017) The medicines refrigerator and the importance of the cold chain in the safe storage of medicines. Nursing Standard, v. 32, n. 6, p. 53. DOI:10.7748/ns.2017.e10960.
Heiskanen, K.; R. Ahonen; P. Karttunen; R. Kanerva e J. Timonen (2015) Medicine shortages study of community pharmacies in finland. Health Policy, v. 119, n. 2, p. 232-238. DOI: 10.1016/j.healthpol.2014.11.001.
Hendrik, G.; J. Hillegersberg; E. De Jong e A. Sikkel (2013) Adoption of wireless sensors in supply chains: a process view anal-ysis of a pharmaceutical cold chain. Journal of theoretical and applied electronic commerce research, v. 8, n. 2, p. 138-154. DOI: 10.4067/S0718-18762013000200011.
Höllein, L.; E. Kaale; Y. Mwalwisi; M. Schulze e U. Holzgrabe (2016) Routine quality control of medicines in developing coun-tries: analytical challenges, regulatory infrastructures and the prevalence of counterfeit medicines in Tanzania. TrAC Trends in Analytical Chemistry, v. 76, p. 60-70. DOI: 10.1016/j.trac.2015.11.009.
Hribernik, K.; T. Warden; K. Thoben e O. Herzog (2010) An internet of things for transport logistics–an approach to connect-ing the information and material flows in autonomous cooperating logistics processes. In Proceedings of the 12th interna-tional conference on information technology & innovation processes of the enterprises, p. 54-67. Disponível em: <http://www.sfb637.uni-bremen.de/pubdb/repository/SFB637-C2-10-004-IC.pdf>. (Acesso em 10/11/2018).
IMShealth (2013) Pharmerging markets Picking a pathway to success. Disponível em: <http://www.pharmatalents.es/assets/files/Pharmerging_white_paper_06_2013.pdf IMShealth>. (Acesso em 05/09/2018)
IMSHealth (2010) MS Institute for Healthcare Informatics. The Use of Medicines in the United States: Review of 2010 April 2011 Report by the IMS Institute for Healthcare Informatics.
Jaberidoost, M.; S. Nikfar; A. Abdollahiasl e R. Dinarvand (2013), Pharmaceutical supply chain risks: a systematic review. DARU Journal of Pharmaceutical Sciences, v. 21, n. 1, p. 69. DOI: 10.1186/2008-2231-21-69.
Jaberidoost, M.; L. Olfat; A. Hosseini; A. Kebriaeezadeh; et al. (2015) Pharmaceutical supply chain risk assessment in Iran using analytic hierarchy process and simple additive weighting methods. Journal of pharmaceutical policy and practice, v. 8, n. 1, p. 9. DOI: 10.1186/s40545-015-0029-3.
Jensen, V. e B. Rappaport (2010) The reality of drug shortages—the case of the injectable agent propofol. New England Jour-nal of Medicine, v. 363, n. 9, p. 806-807, 2010. DOI: 10.1056/NEJMp1005849.
Kanavos, P.; W. Schurer e S. Vogler (2011) The pharmaceutical distribution chain in the European Union: structure and impact on pharmaceutical prices. European Commission, Brussels, Belgium. The London School of economics and political science. London, UK. Disponível em: <http://eprints.lse.ac.uk/51051/A>. (Acesso em 10/11/2018).
Kartoglu, U. e J. Milstien (2014) Tools and approaches to ensure quality of vaccines throughout the cold chain. Expert review of vaccines, v. 13, n. 7, p. 843-854. DOI: 10.1586/14760584.2014.923761.
Kaufmann, J.; R. Miller e J. Cheyne (2011) Vaccine supply chains need to be better funded and strengthened, or lives will be at risk. Health Affairs, v. 30, n. 6, p. 1113-1121. DOI: 10.1377/hlthaff.2011.0368.
Kheir, N.; M. El Hajj; K. Wilbur; et al., (2011) An exploratory study on medications in Qatar homes. Drug healthcare and patient safety, v. 3, p. 99. DOI: 10.2147/DHPS.S25372.
Kelle, P.; J. Woosley e H. Schneider (2012) Pharmaceutical supply chain specifics and inventory solutions for a hospital case. Operations Research for Health Care, v. 1, n. 2-3, p. 54-63. DOI: 10.1016/j.orhc.2012.07.001.
Koster, K. Systems and methods for detecting counterfeit pharmaceutical drugs at the point of retail sale. U.S. Patent, n. 8,543,411, 24 set. 2013. Disponível em:. (Acesso em 10/11/2018).
Kulkarni, N. e S. Niranjan (2013) Multi-echelon network optimization of pharmaceutical cold chains: a simulation study. In Proceedings of the 2013 Winter Simulation Conference: Simulation: Making Decisions in a Complex World, p. 3486-3498. DOI: 10.1109/WSC.2013.6721711.
Kumru, O.; S. Joshi; D. Smith; C. Middaugh; T. Prusik e D. Volkin (2014) Vaccine instability in the cold chain: mechanisms, analysis and formulation strategies. Biologicals, v. 42, n. 5, p. 237-259. DOI: 10.1016/j.biologicals.2014.05.007.
Kumar, N. e A. Jha (2017) Temperature excursion management: A novel approach of quality system in pharmaceutical in-dustry. Saudi Pharmaceutical Journal, v. 25, n. 2, p. 176-183. DOI: 10.1016/j.jsps.2016.07.001.
Laínez, J.; E. Schaefer e G. Reklaitis (2012) Challenges and opportunities in enterprise-wide optimization in the pharmaceuti-cal industry. Computers & Chemical Engineering, v. 47, p. 19-28. DOI: 10.1016/j.compchemeng.2012.07.002.
Lawrence, X.; G. Amidon; M. Khan; S. Hoag; J. Polli; G. Raju e J. Woodcock (2014) Understanding pharmaceutical quality by design. The AAPS journal, v. 16, n. 4, p. 771-783. DOI: 10.1208/s12248-014-9598-3.
Lee, S.; T. O’Connor; X. Yang; C. Cruz; S. Chatterjee; et al., (2015) Modernizing pharmaceutical manufacturing: from batch to continuous production. Journal of Pharmaceutical Innovation, v. 10, n. 3, p. 191-199. DOI: 10.1007/s12247-015-9215-8.
Li, S.; L. Da Xu e X. Wang (2013) Compressed sensing signal and data acquisition in wireless sensor networks and internet of things. IEEE Transactions on Industrial Informatics, v. 9, n. 4, p. 2177-2186. DOI: 10.1109/TII.2012.2189222.
Liu, M.; W. Saman e F. Bruno (2012) Development of a novel refrigeration system for refrigerated trucks incorporating phase change material. Applied Energy, v. 92, p. 336-342. DOI: 10.1016/j.apenergy.2011.10.015.
Liu, X. e W. Wang (2010) Explore the Development of Pharmaceutical Cold-chain Logistics. Logistics Engineering and Manage-ment, v. 11. ISSN: 1674-4993. Disponível em: <http://en.cnki.com.cn/Article_en/CJFDTotal-SPCY201011004.htm>. (Acesso em 10/112018).
Liu, J.; A. Higgins e Y. Tan (2010) IT enabled redesign of export procedure for high-value pharmaceutical product under tempera-ture control: the case of Drug Living Lab. Proceedings of the 11th Annual International Digital Government Research Con-ference on Public Administration Online: Challenges and Opportunities, p. 4-13. Disponível em: <https://dl.acm.org/doi/abs/10.5555/1809874.1809880>. (Acesso em 10/112018).
Luo, H.; M. Zhu; S. Ye; H. Hou; Y. Chen e L. Bulysheva (2016) An intelligent tracking system based on internet of things for the cold chain. Internet Research, v. 26, n. 2, p. 435-445. ISSN 1066-2243. Disponível em: <https://dialnet.unirioja.es/servlet/articulo?codigo=5700862>. (Acesso em10 Nov. 2018).
Marucheck, A.; N. Greis; C. Mena; L. Cai; et al. (2011) Product safety and security in the global supply chain: Issues, challeng-es and research opportunities. Journal of Operations Management, v. 29, n. 7-8, p. 707-720. DOI: 10.1016/j.jom.2011.06.007.
MarketLine (2018a) Global pharmaceuticals. Available online: MarketLine database (Acesso em 23/02/2018).
MarketLine (2018b) Pharmaceuticals in Asia-Pacific. Available online: MarketLine database (Acesso em 23/02/2018).
Masoumi, A.; M. Yu e A. Nagurney (2012) A supply chain generalized network oligopoly model for pharmaceuticals under brand differentiation and perishability. Transportation Research Part E: Logistics and Transportation Review, v. 48, n. 4, p. 762-780. DOI: 10.1016/j.tre.2012.01.001.
McCabe, A.; A. Seiter; A. Diack; C. Herbst; S. Dutta e K. Saleh (2011) Private sector pharmaceutical supply and distribution chan-nels in Africa: a focus on Ghana, Malawi and Mali. The International Bank for Reconstruction and Development. The World Bank NW, Washington. Disponível em: <https://openknowledge.worldbank.org/handle/10986/13590. License: CC BY 3.0 IGO>. (Acesso em 10/11/2018).
Mehralian, G.; A. Gatari; M. Morakabati e H. Vatanpour (2012) Developing a suitable model for supplier selection based on supply chain risks: an empirical study from Iranian pharmaceutical companies. Iranian journal of pharmaceutical research, v. 11, n. 1, p. 209. DOI: 10.22037/IJPR.2012.1077.
Mehralian, G.; F. Zarenezhad e A. Ghatari (2015) Developing a model for an agile supply chain in pharmaceutical industry. International Journal of Pharmaceutical and Healthcare Marketing, v. 9, n. 1, p. 74–91. DOI: 10.1108/IJPHM-09-2013-0050.
Metzner, V.; R. Silva e C. Cugnasca (2014) Modelo de rastreabilidade de medicamentos utilizando identificação por radiofrequên-cia, redes de sensores sem fio e o conceito de internet das coisas. Proceedings of the XXVIII Congresso Nacional de Pesquisa e Ensino em Transporte (p. 1-12). ISBN: 978-85-87-893-17-8. Disponível em: <https://roitier.pro.br/wp-content/uploads/2017/09/AC267.pdf>. (Acesso em 10/11 2018).
Minghetti, P.; D. Pantano; C. Gennari e A. Casiraghi (2014) Regulatory framework of pharmaceutical compounding and actual developments of legislation in Europe. Health Policy, v. 117, n. 3, p. 328-333. DOI: 10.1016/j.healthpol.2014.07.010.
Montoya, G.; J. Benedito; A. Novaes e O. Lima, Jr. (2018) Internet of Things and the risk management approach in the phar-maceutical supply chain. Proceedings of the International Conference on Dynamics in Logistics, p. 284-288. DOI: 10.1007/978-3-319-74225-0_38.
Moreno, A.; I. Angulo; A. Perallos; H. Landaluce; I. Zuazola; L. Azpilicueta e J. Villadangos (2012) IVAN: Intelligent van for the distribution of pharmaceutical drugs. Sensors, v. 12, n. 5, p. 6587-6609. DOI: 10.3390/s120506587.
Možina, M.; D. Tomaževič; S. Leben; F. Pernuš e B. Likar (2010) Digital imaging as a process analytical technology tool for fluid-bed pellet coating process. European Journal of Pharmaceutical Sciences, v. 41 n. 1, p. 156-162. DOI: 10.1016/j.ejps.2010.06.001.
Nagurney, A.; D. Li e L. Nagurney (2013) Pharmaceutical supply chain networks with outsourcing under price and quality competition. International Transactions in Operational Research, v. 20, n.6, p. 859-888. DOI: 10.1111/itor.12031.
Narayana, S.; R. Pati e P. Vrat (2012) Research on management issues in the pharmaceutical industry: a literature review. International Journal of Pharmaceutical and Healthcare Marketing, v. 6, n. 4, p. 351-375. DOI 10.1108/1750612121128323
Narayana, S.; K. Pati e P. Vrat (2014) Managerial research on the pharmaceutical supply chain–A critical review and some insights for future directions. Journal of Purchasing and Supply Management, v. 20, n. 1, p. 18-40. DOI: 10.1016/j.pursup.2013.09.001.
Nelson, E. e H. Huang (2012) Practical considerations in the measurement of the internal relative humidity of pharmaceuti-cal packages with data loggers. Aaps Pharmscitech, v. 12, n. 1, p. 331-336. DOI: 10.1208/s12249-011-9588-z.
Norman, J.; R. Madurawe; C. Moore; M. Khan e A. Khairuzzaman (2017) A new chapter in pharmaceutical manufacturing: 3D-printed drug products. Advanced drug delivery reviews, v. 108, p. 39-50. DOI: 10.1016/j.addr.2016.03.001.
Oli, A.; R. Agu; C. Ihekwereme e C. Esimone (2017) An evaluation of the cold chain technology in South-East, Nigeria using immunogenicity study on the measles vaccines. The Pan African Medical Journal, v. 27, no Suppl 3. DOI: 10.11604/pamj.supp.2017.27.3.11491.
Oró, E.; A. De Gracia; A. Castell; M. Farid e L. Cabeza (2012) Review on phase change materials for cold thermal energy stor-age applications. Applied Energy, v. 99, p. 513-533. DOI: 10.1016/j.rser.2020.110340.
Parmata, U. (2010) Measuring service quality in pharmaceutical supply chain–distributor’s perspective. International Journal of Pharmaceutical and Healthcare Marketing, v. 10, no. 3, p. 258-284. DOI:10.1108/IJPHM-07-2015-0035.
Papert, M.; P. Rimpler e A. Pflaum (2016) Enhancing supply chain visibility in a pharmaceutical supply chain: Solutions based on automatic identification technology. International Journal of Physical Distribution & Logistics Management, v. 46, n. 9, p. 859-884. DOI: 10.1108/IJPDLM-06-2016-0151.
Paul, S.; D. Mytelka; C. Dunwiddie; C. Persinger; B. Munos; S. Lindborg; et al. (2010) How to improve R&D productivity: the pharmaceutical industry's grand challenge. Nature reviews Drug discovery, v. 9, n. 3, p. 203. DOI: 10.1038/nrd3078.
Pharmaceutical Commerce (2016) Property of Healthcare Commerce Media Corporation. Available online: <http://pharmaceuticalcommerce.com/supply-chain-logistics/pharmaceutical-cold-chain-logistics-is-a-12-6-billion-global-industry/>. (Acesso em 20/1/2017)
Polygon (2019) Monitoring Humidity in Pharmaceutical Storage. Available online: <https://www.polygongroup.com/en-US/blog/monitoring-humidity-in-pharmaceutical-storage/>. (Acesso em 20/09/ 2017)
Priyan, S. e R. Uthayakumar (2014) Optimal inventory management strategies for pharmaceutical company and hospital supply chain in a fuzzy–stochastic environment. Operations Research for Health Care, v. 3 n. 4, p. 177-190. DOI: 10.1016/j.orhc.2014.08.001.
Rao, P. (2008) The emergence of the pharmaceutical industry in the developing world and its implications for multinational enterprise strategies. International Journal of Pharmaceutical and Healthcare Marketing, v. 2, n. 2, p. 103-116. DOI: 10.1108/17506120810887907.
Raab, V.; B. Petersen e J. Kreyenschmidt (2011) Temperature monitoring in meat supply chains. British Food Journal, v. 113, n. 10, p. 1267-1289. DOI: 10.1108/00070701111177683.
Rees, H. (2011) Supply chain management in the drug industry: delivering patient value for pharmaceuticals and biologics. John Wiley & Sons. ISBN: 978-0-470-55517-0.
Ringo, S.; V. Mugoyela; E. Kaale and J. Sempombe (2017) Assessment of Medicines Cold Chain Storage Conformity with the World Health Organization Requirements in Health Facilities in Tanzania. Pharmacology & Pharmacy, v. 8, n. 10, p. 325. DOI: 10.4236/pp.2017.810024.
Rossetti, C.; R. Handfield e K. Dooley, (2011) Forces, trends, and decisions in pharmaceutical supply chain management. International Journal of Physical Distribution & Logistics Management, v. 41, n. 6, p. 601-622. DOI:10.1108/0960003111114783.
Ruiz-Garcia, L. e L. Lunadei, (2010) Monitoring cold chain logistics by means of RFID. Sustainable radio frequency identification solutions, v. 2, p. 37-50. ISBN: 978-953-7619-74-9.
Sam, T.; T. Ernest; J. Walsh e J. Williams (2012) European Paediatric Formulation Initiative. A benefit/risk approach towards selecting appropriate pharmaceutical dosage forms–An application for paediatric dosage form selection. International journal of pharmaceutics, v. 435, n. 2, p. 115-123. DOI: 10.1016/j.ijpharm.2012.05.024.
Sangshetti, J.; M. Deshpande; Z. Zaheer; D. Shinde e R. Arote, (2017) Quality by design approach: regulatory need. Arabian Journal of Chemistry, v. 10, p. S3412-S3425. DOI: 10.1016/j.arabjc.2014.01.025.
Shafaat, K.; A. Hussain; B. Kumar; R. Hasan; P. Prabhat e V. KumarYadav (2013) An overview: storage of pharmaceutical products. World journal of pharmacy and pharmaceutical sciences, v. 2, n. 5, p. 2499-2515. ISSN: 2278 –4357. Disponível em: <https://www.wjpps.com/Wjpps_controller/abstract_id/326>. (Acesso em10 Nov. 2018).
Sharif, S.; A. Abduelkarem; H. Bustami; L. Haddad e D. Khalil (2010) Trends of home drug storage and use in different re-gions across the northern United Arab Emirates. Medical Principles and Practice, v. 19 n. 5, p. 355-358. DOI: 10.1159/000316372.
Shen, Y. (2011) Terahertz pulsed spectroscopy and imaging for pharmaceutical applications: a review. International journal of pharmaceutics, v. 417, p. 48-60. DOI: 10.1016/j.ijpharm.2011.01.012.
Shue, Z. (2012) TBA model for surimi shelf life predicting. Jiangxi Food Industry, v. 2, p. 9. CN: 36-1146/T.
Singh, R.; R. Kumar e P. Kumar (2016) Strategic issues in pharmaceutical supply chains: a review. International Journal of Pharmaceutical and Healthcare Marketing, v. 10, n. 3, p. 234-257. DOI: 10.1108/IJPHM-10-2015-0050.
Singh, R. e M. K. Sharma (2014) Selecting competitive supply chain using fuzzy AHP and extent analysis. Journal of Industrial and Production Engineering, v. 31, n. 8, p. 524-538. DOI: 10.1080/21681015.2014.999723.
Smith, J.; M. Lipsitch e J. Almond (2011) Vaccine production, distribution, access, and uptake. The Lancet, v. 378, n. 9789, p. 428-438. DOI: 10.1016/S0140-6736(11)60478-9.
Song, Y.; Y. Bian; M. Petzold; L. Li, e A. Yin (2014) Effects of the National Essential Medicine System in reducing drug prices: an empirical study in four Chinese provinces. Journal of pharmaceutical policy and practice, v. 7, n. 1, p. 12. DOI: 10.1186/2052-3211-7-12.
Susarla, N. e I. Karimi (2012) Integrated supply chain planning for multinational pharmaceutical enterprises. Computers & Chemical Engineering, v. 42, 168-177. DOI: 10.1016/j.compchemeng.2012.03.002.
Taylor, D. (2010). Ecopharmacostewardship–a pharmaceutical industry perspective. In Green and Sustainable Pharmacy (p. 105-126). Springer, Berlin, Heidelberg. DOI: 10.1007/978-3-642-05199-9_7.
Tremblay, M. (2013) Medicines counterfeiting is a complex problem: a review of key challenges across the supply chain. Current drug safety, v. 8, n. 1, p. 43-55. ISSN 1574-8863. Disponível em: <https://www.ingentaconnect.com/contentone/ben/cds/2013/00000008/00000001/art00007>. (Acesso em 10/11/2018).
Thomas, G. Medicinal chemistry: an introduction. John Wiley & Sons, England, 2011, ISBN 978-0-470-02597-0.
Uthayakumar, R. e S. Priyan (2013) Pharmaceutical supply chain and inventory management strategies: Optimization for a pharmaceutical company and a hospital. Operations Research for Health Care, v. 2, n. 3, p. 52-64. DOI: 10.1016/j.orhc.2013.08.001.
Vancea, C. e L. Viman (2011). Wireless data logger for thermal validation systems. Proceedings of the IEEE 17th International Symposium for Design and Technology in Electronic Packaging, p. 295-298. DOI: 10.1109/SIITME.2011.6102739.
Ventola, C. (2011) The drug shortage crisis in the United States: causes, impact, and management strategies. Pharmacy and Therapeutics, v. 36, n. 11, p. 740. Disponível em: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278171/>. (Acesso em 7/09/2017).
Vesper, J.; Ü. Kartogˇlu; R. Bishara e T. Reeves (2010) A case study in experiential learning: Pharmaceutical cold chain man-agement on wheels. Journal of continuing education in the health professions, v. 30, n. 4, p. 229–236. DOI: 10.1002/chp.20087.
Wandalkar, P.; P. Pandit e A. Zite (2013) ABC and VED analysis of the drug store of a tertiary care teaching hospital. Indian Journal of Basic and Applied Medical Research, v. 3, n. 1, p. 126-131. ISSN: 2250-2858. Disponível em: <https://www.ijbamr.com/assets/images/issues/pdf/PDF%20DECEMBER%2013%20%20126-131.pdf.pdf>. (Acesso em 7/11/2017).
Wang, S; F. Tao e Y. Shi (2018) Optimization of Location-Routing Problem for Cold Chain Logistics Considering Carbon Foot-print. International journal of environmental research and public health, v. 15, n. 1, p. 86. DOI: 10.3390/ijerph15010086.
Wobker, M.; A. Mehrotra e B. Carter (2010) Use of commercial data loggers to develop process understanding in pharmaceu-tical unit operations. Journal of Pharmaceutical Innovation, v. 5, n. 4, p. 169-180. DOI: 10.1007/s12247-010-9092-0.
Woodcock, J. e M. Wosinska (2013) Economic and technological drivers of generic sterile injectable drug shortages. Clinical Pharmacology & Therapeutics, v. 93, n. 2, p. 170-176. DOI: 10.1038/clpt.2012.220.
World Health Organization. Annex 5 WHO good distribution practices for pharmaceutical products. 2010.
World Health Statistics (2009). Available online: . (Acesso em 7/09/2017).
Xiao, X.; Q. He; Z. Fu; M. Xu e X. Zhang, (2016) Applying CS and WSN methods for improving efficiency of frozen and chilled aquatic products monitoring system in cold chain logistics. Food Control, v. 60, p. 656-666. DOI: 10.1016/j.foodcont.2015.09.012.
Xutao, L.; C. DongSen; Z. Zhijie e S. Yunqiang (2010) Design of transport vehicles remote monitoring system. Procedings of the 2nd International Conference on Education Technology and Computer, v. 2, p. 310. DOI: 10.1109/ICETC.2010.5529378.
Yadav, P. (2015) Health product supply chains in developing countries: diagnosis of the root causes of underperformance and an agenda for reform. Health Systems & Reform, v.1, n, 2, 142-154. DOI: 10.4161/23288604.2014.968005.
Yu, X.; C. Li; Y. Shi e M. Yu (2010) Pharmaceutical supply chain in China: current issues and implications for health system reform. Health policy, v. 97, n. 1, p. 8. DOI: 10.1016/j.healthpol.2010.02.010.
Zhang, J.; E. Pritchard; X. Hu; T. Valentin; B. Panilaitis; et al., (2012) Stabilization of vaccines and antibiotics in silk and elimi-nating the cold chain. Proceedings of the National Academy of Sciences, v. 109 N. 30, p. 11981-11986. DOI: 10.1073/pnas.1206210109.
Zimmermann, H. (2011) U.S. Patent No. 7,945,455. Washington, DC: U.S. Patent and Trademark Office.
Zipursky, S.; M. Djingarey; J. Lodjo; L. Olodo; et al. (2014) Benefits of using vaccines out of the cold chain: delivering meningi-tis A vaccine in a controlled temperature chain during the mass immunization campaign in Benin. Vaccine, v. 32, n. 13, p. 1431-1435. DOI: 10.1016/j.vaccine.2014.01.038.
Downloads
Publicado
Como Citar
Edição
Seção
Licença
Copyright (c) 2021 giset natalia montoya, Orlando Fontes Lima Jr, Antonio Novaes, Jose Benedito S. Santos Junior, Jaime Andres Cardona Arias
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
Ao submeter um manuscrito para publicação neste periódico, todos os seus autores concordam, antecipada e irrestritamente, com os seguintes termos:
- Os autores mantém os direitos autorais e concedem à Revista TRANSPORTES o direito de primeira publicação do manuscrito, sem nenhum ônus financeiro, e abrem mão de qualquer outra remuneração pela sua publicação pela ANPET.
- Ao ser submetido à Revista TRANSPORTES, o manuscrito fica automaticamente licenciado sob a Licença Creative Commons Attribution, que permite o compartilhamento do trabalho com reconhecimento da autoria e da publicação inicial neste periódico.
- Os autores têm autorização para assumir contratos adicionais separadamente, para distribuição não exclusiva da versão do trabalho publicada neste periódico (ex.: publicar em repositório institucional ou como capítulo de livro), com reconhecimento da publicação inicial nesta revista, desde que tal contrato não implique num endosso do conteúdo do manuscrito ou do novo veículo pela ANPET.
- Os autores têm permissão e são estimulados a publicar e distribuir seu trabalho online (ex.: em repositórios institucionais ou na sua página pessoal) depois de concluído o processo editorial. Como a Revista TRANSPORTES é de acesso livre, os autores são estimulados a usar links para o site da Revista TRANSPORTES nesses casos.
- Os autores garantem ter obtido a devida autorização dos seus empregadores para a transferência dos direitos nos termos deste acordo, caso esses empregadores possuam algum direito autoral sobre o manuscrito. Além disso, os autores assumem toda e qualquer responsabilidade sobre possíveis infrações ao direito autoral desses empregadores, isentando a ANPET e a Revista TRANSPORTES de toda e qualquer responsabilidade neste sentido.
- Os autores assumem toda responsabilidade sobre o conteúdo do trabalho, incluindo as devidas e necessárias autorizações para divulgação de dados coletados e resultados obtidos, isentando a ANPET e a Revista TRANSPORTES de toda e qualquer responsabilidade neste sentido.
